Which of the following statements is true regarding the costs of cancer screening in the United States in 2021?
U.S. Costs for Cancer Screening
Douglas K. Rex, MD, MASGE, reviewing Halpern MT, et al. Ann Intern Med 2024 Aug 6.
This study examined total direct costs in 2021 for initial screening for several cancers in the U.S.: breast cancer (including 40- to 49-year-old women) by mammography; cervical cancer by Pap and human papillomavirus testing; colorectal cancer (CRC) by colonoscopy, flexible sigmoidoscopy, CT colonography, fecal immunochemical testing, and Cologuard; lung cancer by low-dose CT; and prostate cancer (including men aged 55-69 years) by prostate-specific antigen. The 2021 National Health Interview Survey was used to determine the number of screening tests performed, and national cost estimates were utilized. Among the key findings:
COMMENT
It is important to remember that CRC screening is estimated to save costs under certain conditions. Nevertheless, colonoscopy accounts for a substantial portion of all U.S. cancer screening costs, with the majority of this being facility fees for colonoscopies (which comes as no surprise to colonoscopists).
Douglas K. Rex, MD, MASGE
CITATION
Halpern MT, Liu B, Lowy DR, Gupta S, Croswell JM, Doria-Rose VP. The annual cost of cancer screening in the United States. Ann Intern Med 2024 Aug 6. (Epub ahead of print) (https://doi.org/10.7326/m24-0375)
COMMENT
This study affirms important principles for FIT screening. First, cancers detected by FIT remain in an early stage during subsequent screening rounds. Further, increasing the cutoff level of hemoglobin for positive test results reduces sensitivity but does not shift the fraction of detected cancers substantially toward later-stage CRC. Thus, programs can adjust the cutoff to levels appropriate for their colonoscopy resources, and the detected cancers will be in an early stage across a range of hemoglobin thresholds for positive tests.